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1

Correction to An Unfractionated Fucoidan from Ascophyllum nodosum : Extraction, Characterization, and Apoptotic Effects in Vitro

Foley, Sarah A., Szegezdi, Eva, Mulloy, Barbara, Samali, Afshin, Tuohy, Maria G.

Journal:

Journal of Natural Products

Year:

2012

File:

PDF, 114 KB

2012

2

An Unfractionated Fucoidan from Ascophyllum nodosum : Extraction, Characterization, and Apoptotic Effects in Vitro

Foley, Sarah A., Szegezdi, Eva, Mulloy, Barbara, Samali, Afshin, Tuohy, Maria G.

Journal:

Journal of Natural Products

Year:

2011

Language:

english

File:

PDF, 4.85 MB

english, 2011

3

The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis

Dijk, Marianne van, Murphy, Eoin, Morrell, Ruth, Knapper, Steven, O’Dwyer, Michael, Samali, Afshin, Szegezdi, Eva

Journal:

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

4

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL

Tríona Ní Chonghaile, Caoimhín G. Concannon, Eva Szegezdi, Adrienne M. Gorman, Afshin Samali

Journal:

Year:

2006

Language:

english

File:

PDF, 662 KB

english, 2006

5

The mitochondrial death pathway: a promising therapeutic target in diseases

Sanjeev Gupta, George E.N. Kass, Eva Szegezdi, Bertrand Joseph

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

6

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

Adrienne M. Gorman, Eva Szegezdi, Declan J. Quigney, Afshin Samali

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 806 KB

english, 2005

7

Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Death Receptors †

Reis, Carlos R., van der Sloot, Almer M., Szegezdi, Eva, Natoni, Alessandro, Tur, Vicente, Cool, Robbert H., Samali, Afshin, Serrano, Luis, Quax, Wim J.

Journal:

Year:

2009

Language:

english

File:

PDF, 4.25 MB

english, 2009

8

Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling

Sessler, Tamas, Healy, Sandra, Samali, Afshin, Szegezdi, Eva

Journal:

Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 871 KB

english, 2013

9

Correlation between Potassium Channel Expression and Sensitivity to Drug-induced Cell Death in Tumor Cell Lines

Leanza, Luigi, O’Reilly, Paul, Doyle, Anne, Venturini, Elisa, Zoratti, Mario, Szegezdi, Eva, Szabo, Ildiko

Journal:

Current Pharmaceutical Design

Year:

2014

File:

PDF, 407 KB

2014

10

Hypoxia and Ischemia Induce Nuclear Condensation and Caspase Activation in Cardiomyocytes

MARTIN E. O'MAHONEY, SUSAN LOGUE, EVA SZEGEZDI, CATHERINE STENSON-COX, UNA FITZGERALD, AFSHIN SAMALI

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 2.46 MB

2003

11

Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

Gupta, Sanjeev, Cuffe, Lorraine, Szegezdi, Eva, Logue, Susan E., Neary, Catherine, Healy, Sandra, Samali, Afshin

Journal:

International Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

12

Recreating complex pathophysiologies in vitro with extracellular matrix surrogates for anticancer therapeutics screening

Shologu, Naledi, Szegezdi, Eva, Lowery, Aoife, Kerin, Michael, Pandit, Abhay, Zeugolis, Dimitrios I.

Journal:

Drug Discovery Today

Year:

2016

Language:

english

File:

PDF, 342 KB

english, 2016

13

Caspase-12 and ER-Stress-Mediated Apoptosis : The Story So Far

EVA SZEGEZDI, UNA FITZGERALD, AFSHIN SAMALI

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 1.77 MB

2003

14

Targeting AML through DR4 with a novel variant of rhTRAIL

Eva Szegezdi, Carlos R. Reis, Almer M. van der Sloot, Alessandro Natoni, Aoife O’Reilly, Janice Reeve, Robbert H. Cool, Michael O’Dwyer, Steven Knapper, Luis Serrano, Wim J. Quax, Afshin Samali

Journal:

Journal of Cellular and Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

15

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

O’ Reilly, Eimear, Tirincsi, Andrea, Logue, Susan E., Szegezdi, Eva

Journal:

Frontiers in Immunology

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

16

Retinoid receptor-activating ligands are produced within the mouse thymus during postnatal development

Ildikó Kiss, Ralph Rühl, Éva Szegezdi, Britta Fritzsche, Beáta Tóth, Judit Pongrácz, Thomas Perlmann, László Fésüs, Zsuzsa Szondy

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 250 KB

english, 2008

17

Stem cells are resistant to TRAIL receptor-mediated apoptosis

Eva Szegezdi, Aoife O’Reilly, Yeung Davy, Reaz Vawda, Deanna L. Taylor, Mary Murphy, Afshin Samali, Huseyin Mehmet

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 673 KB

english, 2009

18

ER stress contributes to ischemia-induced cardiomyocyte apoptosis

Eva Szegezdi, Angela Duffy, Martin E. O’Mahoney, Susan E. Logue, Louise A. Mylotte, Timothy O’Brien, Afshin Samali

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 308 KB

english, 2006

19

CD95-Mediated Alteration in Hsp70 Levels Is Dependent on Protein Stabilization

Caoimhín G. Concannon, Una FitzGerald, Carina I. Holmberg, Eva Szegezdi, Lea Sistonen and Afshin Samali

Journal:

Cell Stress and Chaperones

Year:

2005

Language:

english

File:

PDF, 462 KB

english, 2005

20

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing

Dhami, Sukhraj Pal S., Kappala, Shanthi S., Thompson, Alexander, Szegezdi, Eva

Journal:

Drug Discovery Today

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

21

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

Dufour, Florent, Rattier, Thibault, Shirley, Sarah, Picarda, Gaelle, Constantinescu, Andrei Alexandru, Morlé, Aymeric, Zakaria, Al Batoul, Marcion, Guillaume, Causse, Sebastien, Szegezdi, Eva, Zajonc,

Journal:

Cell Death & Differentiation

Year:

2017

Language:

english

File:

PDF, 2.42 MB

english, 2017

22

Involvement of planned cell death of necroptosis in cancer treatment by nanomaterials: Recent advances and future perspectives

Sharifi, Majid, Hosseinali, Sara Haji, Saboury, Ali Akbar, Szegezdi, Eva, Falahati, Mojtaba

Journal:

Journal of Controlled Release

Year:

2019

Language:

english

File:

PDF, 2.09 MB

english, 2019

23

Is There a Role for Nuclear Factor κB in Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Resistance?

Amandine Plantivaux, Eva Szegezdi, Afshin Samali, Laurence Egan

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

24

Cell Death in HIV Pathogenesis and Its Modulation by Retinoids

ZSUZSA SZONDY, RÉKA TÓTH, ÉVA SZEGEZDI, UWE REICHERT, PHILIPPE ANCIAN, LÁSZLÓ FÉSÜS

Journal:

Annals of the New York Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 316 KB

english, 2001

25

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

Devalingam Mahalingam, Eva Szegezdi, Maccon Keane, Steven de Jong, Afshin Samali

Journal:

Cancer Treatment Reviews

Year:

2009

Language:

english

File:

PDF, 342 KB

english, 2009

26

NOXA contributes to the sensitivity of PERK-deficient cells to ER stress

Sanjeev Gupta, Zoltan Giricz, Alessandro Natoni, Neysan Donnelly, Shane Deegan, Eva Szegezdi, Afshin Samali

Journal:

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

27

Guiding the Killer and Bringing in Accomplices: Bispecific Antibody Treatment for Malignant Melanoma

Szegezdi, Eva, Leverkus, Martin

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 260 KB

english, 2016

28

Editorial: Death Receptors, Non-apoptotic Signaling Pathways and Inflammation

Szegezdi, Eva, Legembre, Patrick

Journal:

Frontiers in Immunology

Year:

2020

File:

PDF, 113 KB

2020

29

Mediators of endoplasmic reticulum stress-induced apoptosis

Szegezdi, Eva, Logue, Susan E, Gorman, Adrienne M, Samali, Afshin

Journal:

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

30

Activation-induced apoptosis and cell surface expression of Fas (CD95) ligand are reciprocally regulated by retinoic acid receptor α and γ and involve nur77 in T cells

Réka Tóth, Éva Szegezdi, Uwe Reichert, Jean-Michel Bernardon, Serge Michel, Philippe Ancian, Katalin Kis-Tóth, Zsolt Macsári, László Fésüs, Zsuzsa Szondy

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 168 KB

english, 2001

31

Synthetic constrained peptide selectively binds and antagonizes death receptor 5

Johanna Vrielink, Mariette S. Heins, Rita Setroikromo, Eva Szegezdi, Margaret M. Mullally, Afshin Samali, Wim J. Quax

Journal:

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

32

Aspartic Aminopeptidase Is a Novel Biomarker of Aggressive Chronic Lymphocytic Leukemia

Kakodkar, Pramath, More, Sanket, AndrÃ¡s, Kinga, Papakonstantinou, Nikos, Kelly, Sharon, Makrooni, Mohammad Adib, Ortutay, Csaba, Szegezdi, Eva

Journal:

Year:

2020

File:

PDF, 1.48 MB

2020

33

Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively

Réka Tóth, Éva Szegezdi, Gábor Molnár, Janet M. Lord, László Fésüs, Zsuzsa Szondy

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 184 KB

english, 1999

34

Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL

Janice LV Reeve, Eva Szegezdi, Susan E Logue, Tríona Ní Chonghaile, Timothy O’Brien, Thomas Ritter, Afshin Samali

Journal:

Journal of Cellular and Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 596 KB

english, 2007

35

Identification of an inhibitor of caspase activation from heart extracts; ATP blocks apoptosome formation

Afshin Samali, Martin O’Mahoney, Janice Reeve, Susan Logue, Eva Szegezdi, Jill McMahon, Howard O. Fearnhead

Journal:

Year:

2007

Language:

english

File:

PDF, 494 KB

english, 2007

36

Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy

O’Reilly, Paul, Ortutay, Csaba, Gernon, Grainne, O’Connell, Enda, Seoighe, Cathal, Boyce, Susan, Serrano, Luis, Szegezdi, Eva

Journal:

Year:

2014

Language:

english

File:

PDF, 5.39 MB

english, 2014

37

Metabolic Flexibility Permits Mesenchymal Stem Cell Survival in an Ischemic Environment

Louise A. Mylotte, Angela M. Duffy, Mary Murphy, Timothy O'Brien, Afshin Samali, Frank Barry, Eva Szegezdi

Journal:

Year:

2008

Language:

english

File:

PDF, 2.15 MB

english, 2008

38

Decorated Macrocycles via Ring-Closing Double-Reductive Amination. Identification of an Apoptosis Inducer of Leukemic Cells That at Least Partially Antagonizes a 5-HT2 Receptor

Zhou, Jian, Reidy, Mairead, O’Reilly, Ciaran, Jarikote, Dilip V., Negi, Arvind, Samali, Afshin, Szegezdi, Eva, Murphy, Paul V.

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 1.74 MB

english, 2015

39

Correlation between Potassium Channel Expression and Sensitivity to Drug-induced Cell Death in Tumor Cell Lines

Leanza, Luigi, O’Reilly, Paul, Doyle, Anne, Venturini, Elisa, Zoratti, Mario, Szegezdi, Eva, Szabo, Ildiko

Journal:

Current Pharmaceutical Design

Year:

2014

Language:

english

File:

PDF, 407 KB

english, 2014

40

The BH3-mimetic ABT-737 effectively kills acute myeloid leukemia initiating cells

Baev, Denis V., Krawczyk, Janusz, O׳Dwyer, Michael, Szegezdi, Eva

Journal:

Leukemia Research Reports

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

41

Theranostic drug test incorporating the boneâmarrow microenvironment can predict the clinical response of acute myeloid leukaemia to chemotherapy

Dhami, Sukhraj Pal S., Tirincsi, Andrea, Baev, Denis, Krawczyk, Janusz, Quinn, John, Cahill, Mary R., Zeugolis, Dimitrios, Szegezdi, Eva

Journal:

British Journal of Haematology

Year:

2020

File:

PDF, 307 KB

2020

42

BCL-2 modulates the unfolded protein response by enhancingsplicing of X-box binding protein-1

Chonghaile, Triona Ni, Gupta, Sanjeev, John, Mohan, Szegezdi, Eva, Logue, Susan E., Samali, Afshin

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 3.60 MB

english, 2015

43

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

Nathwani, Seema-Maria, Greene, Lisa, Butini, Stefania, Campiani, Giuseppe, Williams, D., Samali, Afshin, Szegezdi, Eva, Zisterer, Daniela

Journal:

International Journal of Oncology

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

44

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

O’ Reilly, Eimear, Dhami, Sukhraj Pal S., Baev, Denis V., Ortutay, Csaba, Halpin-McCormick, Anna, Morrell, Ruth, Santocanale, Corrado, Samali, Afshin, Quinn, John, O’Dwyer, Michael E, Szegezdi, Eva

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.42 MB

english, 2018

45

Targeting Trail Towards the Clinic

Mahalingam, Devalingam, N.A.M. Oldenhuis, Corina, Szegezdi, Eva, J. Giles, Francis, G.E. de Vries, Elisabeth, de Jong, Steven, T. Nawrocki, Steffan

Journal:

Current Drug Targets

Year:

2011

Language:

english

File:

PDF, 267 KB

english, 2011

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